Adjuvant systemic therapy in breast cancer Book Section


Authors: Goldfarb, S.; Zhi, W. I.
Editors: Urban, C.; Rietjens, M.; El-Tamer, M.; Sacchini, V. S.
Article/Chapter Title: Adjuvant systemic therapy in breast cancer
Abstract: Patients with early-stage breast cancer are treated with curative intent. The goal of adjuvant therapy is to improve overall survival [1, 2]. After surgery, although there is no evidence of gross remaining disease, patients still have a risk of relapse from occult micrometastatic disease. The goal of adjuvant systemic therapy is to decrease risk of recurrence while minimizing toxicities and overtreatment. Therefore, it is important to identify patient populations that will benefit most from treatment in order to avoid unnecessary toxicities [3–5]. Patients require different adjuvant therapies based on their risk of recurrence, stage of disease, and tumor biology. In this chapter, we will discuss systemic adjuvant therapy including endocrine therapy, chemotherapy, and HER2-targeted therapy [6, 7]. © Springer International Publishing AG, part of Springer Nature 2013, 2019
Book Title: Oncoplastic and Reconstructive Breast Surgery. 2nd ed
ISBN: 978-3-319-62925-4
Publisher: Springer  
Publication Place: Cham, Switzerland
Date Published: 2019-01-01
Start Page: 179
End Page: 194
Language: English
DOI: 10.1007/978-3-319-62927-8_13
PROVIDER: scopus
DOI/URL:
Notes: Book chapter: 13 -- This chapter can be found under "Part I Basic Principles for Oncoplastic and Reconstructive Breast Surgery" -- Source: Scopus
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MSK Authors
  1. Virgilio Sacchini
    147 Sacchini
  2. Mahmoud B. El-Tamer
    105 El-Tamer
  3. Shari Goldfarb
    151 Goldfarb
  4. Wanqing Iris Zhi
    48 Zhi
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