Laser therapy as a treatment for chronic radiation fibrosis Journal Article
| Authors: | Wilson, B.; Shah, R.; Menzer, C.; Aleisa, A.; Rossi, A. |
| Article Title: | Laser therapy as a treatment for chronic radiation fibrosis |
| Abstract: | Background: Chronic radiation fibrosis (CRF) is a long-term sequala of radiation therapy that has a significant impact on patient quality of life. There is no standard of care or single therapeutic modality that has been found to be consistently effective. Objective: To describe our experience using fractional 10,600 nm carbon dioxide (CO2) laser therapy and vascular laser therapy in a series of patients with CRF. Methods: Patients presenting to the dermatology service for CRF were evaluated for laser therapy eligibility. Patients were eligible if they had a clinical diagnosis of CRF confirmed by physical examination. Results: We identified five patients with CRF treated with fractional ablative CO2 laser and vascular laser. Patients were a median age of 57 years old, and the amount of time between the initiation of radiotherapy and laser treatment ranged between 3 months and 40 years. The satisfactory response was achieved in all cases. Limitations: Lack of standardized laser protocol, small sample size, lack of a control group, different anatomical locations. Conclusion: Fractional ablative and vascular laser therapy may serve as an additional treatment for CRF, leading to functional improvements. © 2022 The Authors. Lasers in Surgery and Medicine published by Wiley Periodicals LLC. |
| Keywords: | osteosarcoma; adult; clinical article; treatment outcome; aged; middle aged; range of motion; case report; quality of life; breast cancer; retrospective study; infant; radiation dose fractionation; clinical evaluation; physical examination; drug therapy; tongue carcinoma; radiation dermatitis; ktp laser; lumpectomy; carbon dioxide; low level laser therapy; laser therapy; procedures; radiation fibrosis syndrome; humans; human; female; article; radiation fibrosis; gas laser; lasers, gas; cancer therapy sequelae; chronic radiation fibrosis; fractional co2 laser; reticulosarcoma |
| Journal Title: | Lasers in Surgery and Medicine |
| Volume: | 55 |
| Issue: | 1 |
| ISSN: | 0196-8092 |
| Publisher: | John Wiley & Sons |
| Date Published: | 2023-01-01 |
| Start Page: | 82 |
| End Page: | 88 |
| Language: | English |
| DOI: | 10.1002/lsm.23617 |
| PUBMED: | 36349748 |
| PROVIDER: | scopus |
| PMCID: | PMC10099494 |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in PubMed and PDF -- Corresponding author is MSK authors: Anthony Rossi -- Source: Scopus |
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