De novo adamantinomatous craniopharyngioma with long-term pre-diagnostic imaging Journal Article
| Authors: | Bou-Nassif, R.; El Ahmadieh, T. Y.; Abou-Mrad, Z.; Rosenblum, M.; Cohen, M. A.; Tabar, V. |
| Article Title: | De novo adamantinomatous craniopharyngioma with long-term pre-diagnostic imaging |
| Abstract: | Adamantinomatous craniopharyngioma has a bimodal age distribution occurring in children aged 5–15 years and less frequently in adults aged 45–60 years. The current embryogenetic hypothesis suggests that adamantinomatous craniopharyngioma (ACP) arises from epithelial remnants of the craniopharyngeal duct or Rathke's pouch. It is thought that this tumor exists early on during childhood but remains indolent, growing very slowly until it is diagnosed incidentally or due to symptoms. Recent reports of de novo development of ACP, however, have challenged this theory. Herein, we present a case of an incidentally discovered de novo adamantinomatous craniopharyngioma that was documented to arise de novo on serial MRIs performed for a different indication. To our knowledge, this is the first report of a middle-aged patient who is diagnosed with a de novo ACP documented with contrast-enhanced MRIs of the sella over a 16-year period. This case challenges our current understanding of the pathophysiology of adamantinomatous craniopharyngioma. © 2023 Elsevier Masson SAS |
| Keywords: | craniopharyngioma; de novo; acp; adamantinomatous |
| Journal Title: | Neurochirurgie |
| Volume: | 69 |
| Issue: | 2 |
| ISSN: | 0028-3770 |
| Publisher: | Elsevier Masson |
| Date Published: | 2023-03-01 |
| Start Page: | 101404 |
| Language: | English |
| DOI: | 10.1016/j.neuchi.2023.101404 |
| PROVIDER: | scopus |
| PUBMED: | 36701980 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 March 2023 -- Source: Scopus |
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226Tabar -
425Rosenblum -
139Cohen -
25El Ahmadieh -
11Abou Mrad
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