Enhancing CD19 chimeric antigen receptor T cells through memory-enriched T cells Editorial

   


Authors: El Marabti, E.; Abdel-Wahab, O.
Title: Enhancing CD19 chimeric antigen receptor T cells through memory-enriched T cells
Abstract: Chimeric antigen receptor T (CAR-T) cells directed against CD19 have transformed the therapy of relapsed/refractory B-cell acute lymphoblastic leukemia (R/R B-ALL). A recent study reports promising activity and safety of CD19 CAR-T cells generated from naïve, stem, and central memory T cells in adults with R/R B-ALL. See related article by Aldoss et al., p. 742. ©2022 American Association for Cancer Research.
Keywords: adult; genetics; acute lymphoblastic leukemia; immunology; precursor cell lymphoblastic leukemia-lymphoma; biological therapy; adoptive immunotherapy; immunotherapy, adoptive; cd19 antigen; antigens, cd19; memory t lymphocyte; humans; human; cell- and tissue-based therapy; memory t cells; receptors, chimeric antigen
Journal Title: Clinical Cancer Research
Volume: 29
Issue: 4
ISSN: 1078-0432
Publisher: American Association for Cancer Research  
Date Published: 2023-02-15
Start Page: 694
End Page: 696
Language: English
DOI: 10.1158/1078-0432.Ccr-22-3232
PUBMED: 36507801
PROVIDER: scopus
PMCID: PMC9957814
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85148249895&doi=10.1158%2f1078-0432.CCR-22-3232&partnerID=40&md5=1e775406e1cbe1a82dd833f1f6b0bc9b
Notes: Editorial -- Export Date: 1 March 2023 -- Source: Scopus
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MSK Authors
  1. Omar Ibrahim Abdel-Wahab
    573 Abdel-Wahab
  2. Ettaib El Marabti
    3 El Marabti
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