The 2020 World Health Organization classification of bone tumors: What radiologists should know Review

  


Authors: Hwang, S.; Hameed, M.; Kransdorf, M.
Review Title: The 2020 World Health Organization classification of bone tumors: What radiologists should know
Abstract: Improved understanding of tumor biology through molecular alteration and genetic advances has resulted in a number of major changes in the 2020 World Health Organization’s (WHO) classification of bone tumors. These changes include the reclassification of the existing tumors and the introduction of several new entities. A new chapter on undifferentiated small round cell sarcomas of bone and soft tissue was added to classify Ewing sarcoma and the family of Ewing-like sarcomas, which share similar histologies but different molecular and clinical behaviors. Knowledge of the current classification of bone tumors is essential to ensure the appropriate recognition of the inherent biological potential of individual osseous lesions for optimal treatment, follow-up, and overall outcome. This article reviews the major changes to the 2020 WHO’s classification of primary bone tumors and the pertinent imaging of selected tumors to highlight these changes. © 2022, The Author(s), under exclusive licence to International Skeletal Society (ISS).
Keywords: bone neoplasms; bone tumor; classification; pathology; diagnostic imaging; tumor marker; ewing sarcoma; sarcoma; radiologist; tumors; bone; imaging; world health organization; soft tissue neoplasms; soft tissue tumor; who classification; update; radiologists; sarcoma, ewing; humans; human; biomarkers, tumor
Journal Title: Skeletal Radiology
Volume: 52
Issue: 3
ISSN: 0364-2348
Publisher: Springer  
Date Published: 2023-03-01
Start Page: 329
End Page: 348
Language: English
DOI: 10.1007/s00256-022-04093-7
PUBMED: 35852560
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85134514857&doi=10.1007%2fs00256-022-04093-7&partnerID=40&md5=711c930ce1ea4e9d2571061f8df4bcc8
Notes: The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PubMed record and PDF. Corresponding author is MSK author Sinchun Hwang -- Export Date: 1 February 2023 -- Source: Scopus
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MSK Authors
  1. Meera Hameed
    281 Hameed
  2. Sinchun Hwang
    96 Hwang
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