Pathology definitions and resection strategies for early colorectal neoplasia: Eastern versus Western approaches in the post-Vienna era Review


Authors: Nishimura, M.; Saito, Y.; Nakanishi, Y.; Shia, J.; Lauwers, G. Y.; Wallace, M. B.
Review Title: Pathology definitions and resection strategies for early colorectal neoplasia: Eastern versus Western approaches in the post-Vienna era
Abstract: There is a well-known discrepancy between East and West classifications of colorectal neoplasm, especially “intramucosal carcinoma,” categorized as subgroup 4.4 in the Vienna classification, usually recognized as high-grade dysplasia in the United States and as carcinoma in situ in Japan. Focusing on management, in the current National Comprehensive Cancer Network algorithm, high-grade dysplasia, carcinoma in situ, and intramucosal carcinoma are managed similarly, whereas submucosal invasion by carcinoma requires en bloc resection. To bridge the differences with regard to these conceptual problems in the definition and management of carcinoma in situ and intramucosal carcinoma, endoscopists and pathologists from Japan and the United States gathered and discussed from their perspectives how to accurately assess specimens of en bloc/piecemeal resection and to effectively predict lymph node metastasis risk. © 2020 American Society for Gastrointestinal Endoscopy
Keywords: cancer surgery; review; united states; follow up; lymph node metastasis; lymphatic metastasis; treatment indication; pathology; colorectal carcinoma; colorectal neoplasms; colorectal tumor; carcinoma in situ; colorectal surgery; japan; pathologist; endoscopic submucosal dissection; humans; human; priority journal; endoscopist; japanese (people)
Journal Title: Gastrointestinal Endoscopy
Volume: 91
Issue: 5
ISSN: 0016-5107
Publisher: Mosby Elsevier  
Date Published: 2020-05-01
Start Page: 983
End Page: 988
Language: English
DOI: 10.1016/j.gie.2019.12.021
PUBMED: 31874160
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 13 January 2023 -- Source: Scopus
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  1. Jinru Shia
    717 Shia