Authors: | Sansa, A.; Valero, C.; Holgado, A.; Vásquez, R.; Quer, M.; Patel, S. G.; León, X. |
Article Title: | External validation of the H-index (host index) in patients with head and neck squamous cell carcinomas |
Abstract: | Background: The aim of the current study is to perform an external validation of the prognostic capacity of the H-index in patients with head and neck squamous cell carcinoma (HNSCC). Methods: Retrospective study of 835 patients with HNSCC located in the oral cavity, oropharynx, hypopharynx, or larynx. Results: When applying the cutoffs proposed in the original description of the H-index (1.5 and 3.5), we observed an orderly and significant decrease in the disease-specific survival and overall survival as H-index increased. Additionally, we were able to observe a decrease in survival as the H-index increased regardless of the location, the extension of the tumor or the type of treatment performed. Conclusion: We have validated the prognostic capacity of the H-index in patients with HNSCC regardless of the location of the primary tumor, the extent of the disease, or the type of treatment performed. © 2022 Wiley Periodicals LLC. |
Keywords: | adult; aged; middle aged; retrospective studies; major clinical study; overall survival; squamous cell carcinoma; carcinoma, squamous cell; cancer patient; pathology; validation study; retrospective study; head and neck neoplasms; cancer specific survival; prognostic factors; oropharynx cancer; larynx cancer; mouth cancer; head and neck tumor; hypopharynx cancer; head and neck squamous cell carcinoma; peripheral blood; oncological parameters; humans; prognosis; human; male; female; article; squamous cell carcinoma of head and neck; h-index; host index |
Journal Title: | Head & Neck |
Volume: | 45 |
Issue: | 1 |
ISSN: | 1043-3074 |
Publisher: | John Wiley & Sons, Inc. |
Date Published: | 2023-01-01 |
Start Page: | 178 |
End Page: | 186 |
Language: | English |
DOI: | 10.1002/hed.27224 |
PUBMED: | 36225167 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 3 January 2023 -- Source: Scopus |