Management of pelvic sarcoma Review


Authors: Lee, J. S.; Kelly, C. M.; Bartlett, E. K.
Review Title: Management of pelvic sarcoma
Abstract: Pelvic sarcomas are a rare and heterogenous group of tumors divided into two groups: soft tissue sarcomas and bone sarcomas. Soft tissue sarcomas of the pelvis include most commonly liposarcoma, leiomyosarcoma, gastrointestinal stromal tumors, malignant peripheral nerve sheath tumors, and solitary fibrous tumors. Bone sarcomas of the pelvis most commonly include osteosarcoma and chondrosarcoma. Multidisciplinary treatment at a center experienced in the treatment of sarcoma is essential. Management is dictated by histologic type and grade. Surgical resection with wide margins is the cornerstone of treatment for pelvic sarcomas, although this is often challenging due to anatomic constraints of the pelvis. Multimodal treatment is critical due to the high risk of local recurrence in the pelvis. © 2022 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology
Keywords: osteosarcoma; bone neoplasms; bone tumor; cancer surgery; cisplatin; doxorubicin; cancer radiotherapy; methotrexate; nuclear magnetic resonance imaging; pelvis; gastrointestinal stromal tumor; imatinib; computer assisted tomography; alkylating agent; pathology; cancer therapy; ifosfamide; sarcoma; needle biopsy; pelvis tumor; pelvic neoplasms; epirubicin; neoadjuvant chemotherapy; trabectedin; leiomyosarcoma; solitary fibrous tumor; anthracycline; rectum tumor; malignant peripheral nerve sheath tumor; chondrosarcoma; pelvis cancer; uterus sarcoma; soft tissue neoplasms; soft tissue tumor; liposarcoma; abdominal radiography; mifamurtide; bladder; cumulative incidence; randomized controlled trial (topic); phase 2 clinical trial (topic); phase 3 clinical trial (topic); multicenter study (topic); pelvis radiography; acetabulum; image guided biopsy; humans; human; article; multidisciplinary team; gluteus muscle; avapritinib
Journal Title: European Journal of Surgical Oncology
Volume: 48
Issue: 11
ISSN: 0748-7983
Publisher: Elsevier Inc.  
Date Published: 2022-11-01
Start Page: 2299
End Page: 2307
Language: English
DOI: 10.1016/j.ejso.2022.09.011
PUBMED: 36195471
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 3 January 2023 -- Source: Scopus
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  1. Ciara Marie Kelly
    89 Kelly