Authors: | Kuba, M. G.; Brogi, E. |
Review Title: | Update on lobular lesions of the breast |
Abstract: | The current histological classification of in-situ and invasive lobular carcinomas (ILCs) includes different morphological variants, some of which have been recently described. In this review, we will focus upon: (i) the diagnostic criteria of non-invasive lobular neoplasia and treatment implications across different countries; (ii) utility and limitations of immunohistochemistry; (iii) recently described variants of ILC; and (iv) the significance of lobular differentiation in invasive carcinoma for clinical management. © 2022 John Wiley & Sons Ltd. |
Keywords: | breast; e-cadherin; lobular carcinoma in situ; invasive lobular carcinoma |
Journal Title: | Histopathology |
Volume: | 82 |
Issue: | 1 |
ISSN: | 0309-0167 |
Publisher: | Wiley Blackwell |
Date Published: | 2023-01-01 |
Start Page: | 36 |
End Page: | 52 |
Language: | English |
DOI: | 10.1111/his.14829 |
PUBMED: | 36482279 |
PROVIDER: | scopus |
PMCID: | PMC9752180 |
DOI/URL: | |
Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Corresponding author is MSK author: Maria Gabriela Kuba -- Source: Scopus |