How 3 academic centers prescribe stereotactic body radiation therapy for primary lung cancer Journal Article

   


Authors: De Leo, A. N.; Dagan, R.; Amdur, R. J.; Yeung, A. R.; Li, J.; Brooks, E. D.; Gilbo, P.; Gomez, D.; Chang, J. Y.; Ning, M.
Article Title: How 3 academic centers prescribe stereotactic body radiation therapy for primary lung cancer
Abstract: Stereotactic body radiation therapy (SBRT) is commonly used to treat early-stage, node-negative primary lung cancer, but society guidelines provide limited information regarding several technical aspects of SBRT, leading to potential variation in practice. In this report, we present the technical details used by 3 academic institutions when treating a solitary primary lung tumor up to 5 cm in dimension with curative-intent SBRT. We provide specifications outlined in major active or recently completed clinical trials. Among the participating institutions, we discovered multiple divergences in treatment parameters, including, but not limited to, prescription dose and desired degree of heterogeneity within the target volume. It is unclear to what extent these differences in parameters might affect tumor control or toxicity, but updated consensus guidelines addressing the relevant SBRT prescription details may help standardize practice patterns. © 2022 American Society for Radiation Oncology
Keywords: controlled study; treatment planning; radiation dose; clinical practice; consensus; tumor volume; lung neoplasms; health survey; lung cancer; practice guideline; pathology; lung tumor; radiosurgery; lung; consensus development; cancer control; stereotactic body radiation therapy; university hospital; procedures; planning target volume; social participation; humans; human; article
Journal Title: Practical Radiation Oncology
Volume: 12
Issue: 6
ISSN: 1879-8519
Publisher: Elsevier Inc.  
Date Published: 2022-11-01
Start Page: 496
End Page: 503
Language: English
DOI: 10.1016/j.prro.2022.02.006
PUBMED: 35219881
PROVIDER: scopus
PMCID: PMC11853861
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85134786324&doi=10.1016%2fj.prro.2022.02.006&partnerID=40&md5=152855156ba94354140bcded4eb65272
Notes: Article -- Export Date: 1 December 2022 -- Source: Scopus
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MSK Authors
  1. Daniel R Gomez
    244 Gomez
  2. Philip William Gilbo
    4 Gilbo
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