Pancreatic neuroendocrine neoplasms: A 2022 update for radiologists Review


Authors: Galgano, S. J.; Morani, A. C.; Gopireddy, D. R.; Sharbidre, K.; Bates, D. D. B.; Goenka, A. H.; Arif-Tiwari, H.; Itani, M.; Iravani, A.; Javadi, S.; Faria, S.; Lall, C.; Bergsland, E.; Verma, S.; Francis, I. R.; Halperin, D. M.; Chatterjee, D.; Bhosale, P.; Yano, M.
Review Title: Pancreatic neuroendocrine neoplasms: A 2022 update for radiologists
Abstract: Pancreatic neuroendocrine neoplasms (PaNENs) are a unique group of pancreatic neoplasms with a wide range of clinical presentations and behaviors. Given their heterogeneous appearance and increasing detection on cross-sectional imaging, it is essential that radiologists understand the variable presentation and distinctions PaNENs display compared to other pancreatic neoplasms. Additionally, some of these neoplasms may be hormonally functional, and it is imperative that radiologists be aware of the common clinical presentations of hormonally active PaNENs. Knowledge of PaNEN pathology and treatments may influence which imaging modality is optimal for each patient. Each imaging modality used for PaNENs has distinct advantages and disadvantages, particularly in different treatment settings. Thus, the focus of this manuscript is to provide an update for the radiologist on PaNEN pathology, imaging, and treatments. © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.
Keywords: review; systemic therapy; pancreatic neoplasms; cancer staging; antineoplastic agent; cancer grading; pancreas; tumor differentiation; pathology; diagnostic imaging; tumor marker; cancer therapy; cell heterogeneity; radiologist; pancreas tumor; pancreas islet cell tumor; neuroendocrine; procedures; cancer prognosis; radiologists; humans; human; panen
Journal Title: Abdominal Radiology
Volume: 47
Issue: 12
ISSN: 2366-004X
Publisher: Springer  
Date Published: 2022-12-01
Start Page: 3962
End Page: 3970
Language: English
DOI: 10.1007/s00261-022-03466-9
PUBMED: 35244755
PROVIDER: scopus
DOI/URL:
Notes: Review -- Export Date: 1 December 2022 -- Source: Scopus
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  1. David Dawson Bartlett Bates
    53 Bates