Concurrent pulmonary Aspergillus and non-Aspergillus mold infections in allogeneic hematopoetic cell transplant recipients Journal Article
| Authors: | Gali, V.; Kaltsas, A.; Cintrón, M.; Papanicolaou, G. A.; Lee, Y. J. |
| Article Title: | Concurrent pulmonary Aspergillus and non-Aspergillus mold infections in allogeneic hematopoetic cell transplant recipients |
| Abstract: | Patients with hematologic malignancies and recipients of hematopoietic cell transplantation (HCT) are at high risk for invasive mold infections (IMIs). However, risk factors and clinical manifestations are similar between Aspergillus spp. and non-Aspergillus spp. IMIs. Herein, we describe three HCT recipients who had probable invasive pulmonary Aspergillus and non-Aspergillus co-infections. Antifungal agents were changed to voriconazole in two cases where, ultimately, non-Aspergillus molds were diagnosed after these patients died. Our cases highlight the need for better fungal diagnostics in immunocompromised patients. Clinicians should be aware that Aspergillus spp. and non-Aspergillus spp. IMIs can occur concurrently. © 2022 Elsevier B.V. |
| Keywords: | hematopoietic cell transplantation; concurrent infections; invasive mold infections |
| Journal Title: | Transplant Immunology |
| Volume: | 76 |
| ISSN: | 0966-3274 |
| Publisher: | Elsevier BV |
| Date Published: | 2023-02-01 |
| Start Page: | 101745 |
| Language: | English |
| DOI: | 10.1016/j.trim.2022.101745 |
| PUBMED: | 36379375 |
| PROVIDER: | scopus |
| PMCID: | PMC9839572 |
| DOI/URL: | |
| Notes: | Article -- The MSK Cancer Center Support Grant (P30 CA008748) is acknowledged in the PDF -- Corresponding author is MSK author Yeon Joo Lee -- Export Date: 1 December 2022 -- Source: Scopus |
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