| Abstract: |
Magnetic resonance imaging (MRI) is an essential tool in breast imaging with a high diagnostic accuracy for breast cancer diagnosis and several other established indications. The diagnostic value of breast MRI is based on its ability to provide not only morphological but also functional and metabolic information that can be used for both the detection and characterization of breast tumors. The combined application of different MRI parameters is defined as multiparametric MRI (mpMRI). There is conclusive data that mpMRI is superior to single-parametric MRI of the breast as it may simultaneously provide a multitude of information, such as neo-angiogenesis, cellularity, tumor microenvironment, metabolite concentration, receptor status, tissue pH, and oxygenation, that can be used for an improved lesion evaluation. mpMRI can be performed at 1.5T, 3T, and event at 7T field strengths, although for research use only, using different combinations of MRI parameters. This review provides a comprehensive overview on the current clinical applications and emerging techniques of mpMRI of the breast. We will discuss the role of mpMRI for diagnosis, prognosis, response assessment, and screening of high-risk population and provide an outlook on the use of radiomics in this context. © 2022, Springer Nature Switzerland AG. |
