DeepLIIF: An online platform for quantification of clinical pathology slides Conference Paper


Authors: Ghahremani, P.; Marino, J.; Dodds, R.; Nadeem, S.
Title: DeepLIIF: An online platform for quantification of clinical pathology slides
Conference Title: 2022 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)
Abstract: In the clinic, resected tissue samples are stained with Hematoxylin-and-Eosin (H&E) and/or Immunhistochem-istry (IHC) stains and presented to the pathologists on glass slides or as digital scans for diagnosis and assess-ment of disease progression. Cell-level quantification, e.g. in IHC protein expression scoring, can be extremely in-efficient and subjective. We present DeepLIIF (https://deepliif.org), a first free online platform for ef-ficient and reproducible IHC scoring. DeepLIIF outper-forms current state-of-the-art approaches (relying on man-ual error-prone annotations) by virtually restaining clinical IHC slides with more informative multiplex immunofluores-cence staining. Our DeepLIIF cloud-native platform sup-ports (1) more than 150 proprietary/non-proprietary input formats via the Bio-Formats standard, (2) interactive ad-justment, visualization, and downloading of the IHC quan-tification results and the accompanying restained images, (3) consumption of an exposed workflow API programmat-ically or through interactive plugins for open source whole slide image viewers such as QuPath/ImageJ, and (4) auto scaling to efficiently scale GPU resources based on user demand. © 2022 IEEE.
Journal Title Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition
Conference Dates: 2022 Jun 18-24
Conference Location: New Orleans, LA
ISBN: 2575-7075
Publisher: IEEE  
Date Published: 2022-01-01
Start Page: 21367
End Page: 21373
Language: English
DOI: 10.1109/cvpr52688.2022.02071
PROVIDER: scopus
DOI/URL:
Notes: Conference Paper -- (ISBN: 978-1-6654-6946-3) -- Export Date: 1 December 2022 -- Source: Scopus
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  1. Saad Nadeem
    50 Nadeem
  2. Joseph Marino
    5 Marino