Clinical manufacture of FT819: Use of a clonal multiplexed-engineered master induced pluripotent stem cell line to mass produce off-the-shelf CAR T-cell therapy Meeting Abstract


Authors: Yuan, X.; Clarke, R.; Lai, Y. S.; Chang, C. W.; Yang, B. H.; Hsia, G.; Abujarour, R.; Lee, T.; van der Stegen, S.; Shaked, H.; Jalloh, A.; Moreno, S.; O'Rourke, J.; Sung, E.; Gutierrez, A.; Rezner, B.; Eberhart, M.; Magdaleno, R.; Wang, X.; Senechal, B.; Sikder, D. S.; Farnan, D.; Plavsic, M.; Bressi, J.; Rivière, I.; Valamehr, B.
Abstract Title: Clinical manufacture of FT819: Use of a clonal multiplexed-engineered master induced pluripotent stem cell line to mass produce off-the-shelf CAR T-cell therapy
Meeting Title: 63rd Annual Meeting of the American Society of Hematology (ASH)
Keywords: cancer immunotherapy; cell therapy; pluripotent stem cell; allogeneic; induced; production; ipsc; cd19; cgmp; engineered; car-t; manufacturing; off-the-shelf; clonal master ipsc line; ft819
Journal Title: Blood
Volume: 138
Issue: Suppl. 1
Meeting Dates: 2021 Dec 11-14
Meeting Location: Atlanta, GA
ISSN: 0006-4971
Publisher: American Society of Hematology  
Date Published: 2021-11-23
Language: English
ACCESSION: WOS:000736398807004
DOI: 10.1182/blood-2021-152985
PROVIDER: wos
Notes: Meeting Abstract: 1766 -- Hybrid meeting, also took place online -- Source: Wos
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  1. Isabelle C Riviere
    240 Riviere
  2. Xiuyan Wang
    118 Wang
  3. Devanjan Sikder Sikder
    12 Sikder