CD19 epitope masking by tafasitamab leads to delays in subsequent use of CD19 CAR T-cell therapy in two patients with aggressive mature B-cell lymphomas Correspondence


Authors: Fitzgerald, K. N.; Quesada, A. E.; von Keudell, G.; Raj, S.; Lewis, N. E.; Dogan, A.; Salles, G.; Palomba, M. L.
Title: CD19 epitope masking by tafasitamab leads to delays in subsequent use of CD19 CAR T-cell therapy in two patients with aggressive mature B-cell lymphomas
Keywords: immunohistochemistry; adult; clinical article; human tissue; aged; middle aged; primary tumor; human cell; lenalidomide; cancer recurrence; case report; advanced cancer; cancer growth; flow cytometry; letter; antigen expression; phenotype; b lymphocyte; hospitalization; b cell lymphoma; germinal center; death; cancer cell; lymphoma cell; epitope; sepsis; imaging; follicular lymphoma; lymph node biopsy; cd19 antigen; cell surface; molecularly targeted therapy; fine needle aspiration biopsy; diffuse large b cell lymphoma; human; male; female; chimeric antigen receptor t-cell immunotherapy; masking; tafasitamab
Journal Title: Leukemia and Lymphoma
Volume: 63
Issue: 3
ISSN: 1042-8194
Publisher: Taylor & Francis Group  
Date Published: 2022-01-01
Start Page: 751
End Page: 754
Language: English
DOI: 10.1080/10428194.2021.1992622
PUBMED: 34949132
PROVIDER: scopus
DOI/URL:
Notes: Letter -- Export Date: 1 April 2022 -- Funding details: National Institutes of Health, NIH -- Funding details: National Cancer Institute, NCI, P30 CA008748, P50 CA192937 -- Funding details: Roche -- Funding details: Takeda Pharmaceuticals U.S.A., TPUSA -- Funding text 1: We would like to thank the Janice Stanton Fund for supporting this work. This work was supported in part through the NIH/NCI Cancer Center Support Grant [P30 CA008748] and MSK Lymphoma SPORE [P50 CA192937] (A.D.) and Farmer Family Foundation (A.D.). -- Funding text 2: Ahmet Dogan reports personal fees from Corvus Pharmaceuticals, Physicians’ Education Resource, Seattle Genetics, Takeda, Roche, EUSAPharma, PeerView, and research support from Roche and Takeda. -- Source: Scopus
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MSK Authors
  1. Maria Lia Palomba
    416 Palomba
  2. Ahmet Dogan
    456 Dogan
  3. Sandeep Sunder Raj
    19 Raj
  4. Gilles Andre Salles
    272 Salles
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