Phollow the phosphoinositol: Actin dynamics at the B cell immune synapse Editorial


Authors: Wang, M. S.; Huse, M.
Title: Phollow the phosphoinositol: Actin dynamics at the B cell immune synapse
Abstract: Actin remodeling promotes B cell activation by enabling B cell antigen receptor clustering in the immune synapse. In the current issue of JCB, Droubi et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202112018) find that this process is initiated by the lipid phosphatase INPP5B, which shapes synaptic actin architecture by locally depleting phosphatidylinositol 4,5 bisphosphate. © 2022 Wang and Huse.
Journal Title: Journal of Cell Biology
Volume: 221
Issue: 9
ISSN: 0021-9525
Publisher: Rockefeller University Press  
Date Published: 2022-09-05
Start Page: e202208015
Language: English
DOI: 10.1083/jcb.202208015
PUBMED: 35969858
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 1 September 2022 -- Source: Scopus
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  1. Morgan Huse
    68 Huse
  2. Mitchell S Wang
    2 Wang