Authors: | Wang, M. S.; Huse, M. |
Title: | Phollow the phosphoinositol: Actin dynamics at the B cell immune synapse |
Abstract: | Actin remodeling promotes B cell activation by enabling B cell antigen receptor clustering in the immune synapse. In the current issue of JCB, Droubi et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202112018) find that this process is initiated by the lipid phosphatase INPP5B, which shapes synaptic actin architecture by locally depleting phosphatidylinositol 4,5 bisphosphate. © 2022 Wang and Huse. |
Journal Title: | Journal of Cell Biology |
Volume: | 221 |
Issue: | 9 |
ISSN: | 0021-9525 |
Publisher: | Rockefeller University Press |
Date Published: | 2022-09-05 |
Start Page: | e202208015 |
Language: | English |
DOI: | 10.1083/jcb.202208015 |
PUBMED: | 35969858 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Article -- Export Date: 1 September 2022 -- Source: Scopus |