A pilot study of micro-CT-based whole tissue imaging (WTI) on endoscopic submucosal dissection (ESD) specimens Journal Article
| Authors: | Sakamoto, H.; Nishimura, M.; Teplov, A.; Leung, G.; Ntiamoah, P.; Cesmecioglu, E.; Kawata, N.; Ohnishi, T.; Kareem, I.; Shia, J.; Yagi, Y. |
| Article Title: | A pilot study of micro-CT-based whole tissue imaging (WTI) on endoscopic submucosal dissection (ESD) specimens |
| Abstract: | Endoscopic submucosal dissection can remove large superficial gastrointestinal lesions in en bloc. A detailed pathological evaluation of the resected specimen is required to assess the risk of recurrence after treatment. However, the current method of sectioning specimens to a thickness of a few millimeters does not provide information between the sections that are lost during the preparation. In this study, we have produced three-dimensional images of the entire dissected lesion for nine samples by using micro-CT imaging system. Although it was difficult to diagnose histological type on micro-CT images, it successfully evaluates the extent of the lesion and its surgical margins. Micro-CT images can depict sites that cannot be observed by the conventional pathological diagnostic process, suggesting that it may be useful to use in a complementary manner. |
| Keywords: | resection; computed tomography; cancer |
| Journal Title: | Scientific Reports |
| Volume: | 12 |
| ISSN: | 2045-2322 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2022-06-14 |
| Start Page: | 9889 |
| Language: | English |
| ACCESSION: | WOS:000811293500060 |
| DOI: | 10.1038/s41598-022-13907-6 |
| PROVIDER: | wos |
| PMCID: | PMC9198046 |
| PUBMED: | 35701447 |
| Notes: | Author Kareem Ibrahim's first name and last name are swapped in the PDF and publisher record -- Source: Wos |
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
Related MSK Work