The association between Memorial Sloan Kettering Frailty Index with 30-day survival among patients aged ≥ 75 with cancer and COVID-19 Journal Article
| Authors: | Kim, S. J.; Fessele, K. L.; Tin, A. L.; Malling, C.; Litchfield, H.; Korc-Grodzicki, B.; Shahrokni, A. |
| Article Title: | The association between Memorial Sloan Kettering Frailty Index with 30-day survival among patients aged ≥ 75 with cancer and COVID-19 |
| Abstract: | Background: Advanced age and multiple comorbidities have been established as a risk factor for more severe disease and increased mortality among patients with COVID-19, yet the impact of frailty in patients with cancer 75 years and older who are admitted, remains unclear. Methods: To better understand the clinical presentation and course of illness for this population, we conducted a chart review of patients with cancer age 75 and older who were admitted to a comprehensive cancer center within 72 h of a confirmed COVID-19 diagnosis over a three-month period (March 1, 2020-May 31, 2020). Frequency and proportion of characteristics were reported. We additionally assessed the association between frailty and 30-day mortality using univariable logistic regression. Results: Our cohort consisted of 70 patients. We found evidence that increased frailty based on MSK-FI was associated with increased risk of 30-day mortality (OR 1.37, 95% CI 1.00, 1.87; p-value = 0.051), though this did not meet conventional levels of significance. Conclusion: Our analysis showed evidence of some association between degree of frailty and 30-day survival among older patients with cancer aged ≥75 who were admitted with COVID-19 infection. This finding illustrates the importance of frailty screening in the care management of older patients with cancer and COVID-19. © 2022 Elsevier Ltd |
| Keywords: | aging; frailty; cancer; covid-19 |
| Journal Title: | Journal of Geriatric Oncology |
| Volume: | 13 |
| Issue: | 4 |
| ISSN: | 1879-4068 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2022-05-01 |
| Start Page: | 416 |
| End Page: | 419 |
| Language: | English |
| DOI: | 10.1016/j.jgo.2021.12.014 |
| PUBMED: | 34955444 |
| PROVIDER: | scopus |
| PMCID: | PMC8687748 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 June 2022 -- Source: Scopus |
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