Rectal MRI radiomics inter- and intra-reader reliability: Should we worry about that? Review
| Authors: | Kwok, H. C.; Charbel, C.; Danilova, S.; Miranda, J.; Gangai, N.; Petkovska, I.; Chakraborty, J.; Horvat, N. |
| Review Title: | Rectal MRI radiomics inter- and intra-reader reliability: Should we worry about that? |
| Abstract: | Purpose: The aim of this review paper is to summarize the current literature regarding inter- and intra-reader reliability of radiomics on rectal MRI. Methods: Original studies examining treatment response prediction in patients with rectal cancer following neoadjuvant therapy using rectal MRI-based radiomics between January 2010 and December 2021 were identified via a PubMed/Medline search. Studies in which intra- and/or inter-reader reliability had been reported were included in this review. Results: Thirteen studies were selected, with an average number of patients of 145 (range, 20–649). All included studies evaluated T2-weighted imaging (T2WI) and/or diffusion-weighted imaging (DWI) sequences, while 3/13 (23%) also evaluated the contrast-enhanced T1-weighted imaging (T1WI) sequence. Most of the selected studies involved two readers (10/13, 77%), 6/13 (46%) studies used baseline MRI only, 1/13 (8%) study used restaging MRI only, and 6/13 (46%) used both. Segmentation was performed manually in 10/13 (77%) studies, and in a slight majority of studies (7/13, 54%), the entire tumor volume (3D VOI) was segmented, while 4/13 (31%) studies segmented the 2D ROI and 2/13 (15%) segmented both. Intraclass correlation coefficient (ICC) on intra-reader agreement varied from 0.73 to 0.93. ICC to assess inter-reader varied from 0.60 to 0.99. Overall, features obtained from baseline rectal MRI, using 3D VOI and first-order features, had higher agreement. Conclusion: Based on our qualitative assessment of a small number of non-dedicated studies, there seems to be good reliability, particularly among low-order features extracted from the entire tumor volume using baseline MRI; however, direct evidence remains scarce. More targeted research in this area is required to quantitatively verify reliability, and before these novel radiomic techniques can be clinically adopted. Graphical abstract: [Figure not available: see fulltext.]. © 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. |
| Keywords: | retrospective studies; nuclear magnetic resonance imaging; magnetic resonance imaging; reproducibility; reproducibility of results; pathology; retrospective study; reliability; rectal neoplasms; rectum tumor; diffusion weighted imaging; diffusion magnetic resonance imaging; rectal cancer; agreement; procedures; machine learning; humans; human |
| Journal Title: | Abdominal Radiology |
| Volume: | 47 |
| Issue: | 6 |
| ISSN: | 2366-004X |
| Publisher: | Springer |
| Date Published: | 2022-06-01 |
| Start Page: | 2004 |
| End Page: | 2013 |
| Language: | English |
| DOI: | 10.1007/s00261-022-03503-7 |
| PUBMED: | 35366088 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Review -- Export Date: 1 June 2022 -- Source: Scopus |
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