Authors: | Lebow, E. S.; Bussière, M. R.; Shih, H. A. |
Editor: | Strowd, R. E. 3rd |
Article/Chapter Title: | Introduction to radiation therapy |
Abstract: | Radiation therapy kills cancer cells through induction of DNA damage, most importantly the double-strand DNA break, which is difficult to accurately repair and often lethal. The total dose of radiation (measured Gray) is typically divided into smaller daily doses, referred to as fractions. Radiation therapy most commonly utilizes photons, which are high-energy x-rays, but may also utilize protons in certain clinical scenarios. The physical properties of protons allow for reduced dose of radiation to normal tissues adjacent to the tumor target compared with photons. © 2021 Elsevier Inc. All rights reserved. |
Keywords: | dna damage; radiation therapy; stereotactic radiosurgery; photon; proton; external beam radiation therapy; whole brain radiation therapy |
Book Title: | Neuro-Oncology for the Clinical Neurologist |
ISBN: | 978-0-323-69494-0 |
Publisher: | Elsevier Inc. |
Publication Place: | Philadelphia, PA |
Date Published: | 2020-12-04 |
Start Page: | 28 |
End Page: | 37 |
Language: | English |
DOI: | 10.1016/b978-0-323-69494-0.00003-8 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Book Chapter -- Export Date: 2 May 2022 -- Source: Scopus -- This is chapter 3 in the book in "Section 1. Basic principles of neuro-oncology" |