Inflammation and cancer: IL-6 and STAT3 complete the link Journal Article
| Authors: | Bromberg, J.; Wang, T. C. |
| Article Title: | Inflammation and cancer: IL-6 and STAT3 complete the link |
| Abstract: | There is growing evidence that tumors are sustained and promoted by inflammatory signals from the surrounding microenvironment. Two papers by Grivennikov et al. and Bollrath et al. in this issue of Cancer Cell demonstrate the importance of the interleukin-6 family of proinflammatory cytokines and their downstream effector STAT3 in colitis-associated colon cancer. © 2009 Elsevier Inc. All rights reserved. |
| Keywords: | signal transduction; protein phosphorylation; cancer risk; nonhuman; colorectal cancer; animals; stat3 protein; models, biological; tumor volume; inflammation; colonic neoplasms; immunoglobulin enhancer binding protein; carcinogenesis; cell type; cancer cell; interleukin 6; interleukin-6; i kappa b kinase beta; colitis; enteritis; intestine epithelium cell; short survey; autocrine communication; cytokine receptor gp130; stat3 transcription factor |
| Journal Title: | Cancer Cell |
| Volume: | 15 |
| Issue: | 2 |
| ISSN: | 1535-6108 |
| Publisher: | Cell Press |
| Date Published: | 2009-02-03 |
| Start Page: | 79 |
| End Page: | 80 |
| Language: | English |
| DOI: | 10.1016/j.ccr.2009.01.009 |
| PUBMED: | 19185839 |
| PROVIDER: | scopus |
| PMCID: | PMC3684978 |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 38" - "Export Date: 30 November 2010" - "CODEN: CCAEC" - "Source: Scopus" |
