High-intensity focused ultrasound ablation of muscle in an anticoagulated swine model Journal Article
| Authors: | Kaye, E. A.; Solomon, S. B.; Gutta, N. B.; Monette, S.; Ezell, P. C.; Maybody, M. |
| Article Title: | High-intensity focused ultrasound ablation of muscle in an anticoagulated swine model |
| Abstract: | Introduction: Image-guided non-invasive high-intensity focused ultrasound (HIFU) has been gaining recognition in treating musculoskeletal tumors and desmoids. However, there is no consensus on the appropriate perioperative management for patients on ongoing anticoagulation who undergo HIFU ablation. Material and methods: Image-guided HIFU treatment was performed in swine on an ongoing oral anticoagulation protocol (N = 5) in two treatment sessions seven days apart. On day one, a total of twenty locations were ablated, and on day eight, ten more muscle ablations were performed, and the animals were euthanized. Imaging, clinical examination, and histopathology were performed to investigate treated tissue for bleeding. Results: Imaging, clinical examination, and histopathology revealed either no bleeding or, in some samples, only small scattered cavities (0.2–2 mm in diameter) filled with blood. Conclusion: Noninvasive HIFU ablation of muscle may not require a coagulation profile within normal limits. © 2020 Society of Medical Innovation and Technology. |
| Keywords: | animal; animals; high intensity focused ultrasound; anticoagulation; swine; pig; muscle; muscles; thermal ablation; humans; human; fus; hifu; high-intensity focused ultrasound ablation; swine model |
| Journal Title: | Minimally Invasive Therapy and Allied Technologies |
| Volume: | 31 |
| Issue: | 1 |
| ISSN: | 1364-5706 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 2022-01-01 |
| Start Page: | 89 |
| End Page: | 93 |
| Language: | English |
| DOI: | 10.1080/13645706.2020.1760301 |
| PUBMED: | 32491939 |
| PROVIDER: | scopus |
| PMCID: | PMC10288204 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 March 2022 -- Source: Scopus |
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