Ablation of the sacroiliac joint using MR-guided high intensity focused ultrasound: A preliminary experiment in a swine model Journal Article
| Authors: | Kaye, E. A.; Maybody, M.; Monette, S.; Solomon, S. B.; Gulati, A. |
| Article Title: | Ablation of the sacroiliac joint using MR-guided high intensity focused ultrasound: A preliminary experiment in a swine model |
| Abstract: | Background: Dysfunction of the Sacroiliac Joint (SIJ) is one of the key sources of low back pain. For prolonged pain relief, some patients undergo fluoroscopic guided radio-frequency (RF) ablation of SIJ, during which a number of RF probes are inserted to create thermal lesions that disrupt the posterior sacral nerve supply. This procedure is minimally invasive, laborious, time-consuming and costly. To study if High Intensity Focused Ultrasound (HIFU) ablation is a feasible alternative approach to SIJ pain treatment, we performed experiments using HIFU to ablate SIJ in the swine model. Methods: Three female Yorkshire swine (36, 35.2 and 34 kg) underwent bilateral Magnetic Resonance guided HIFU (MRgHIFU) ablation of the SIJs. Treatment assessment was performed using contrast-enhanced imaging, histopathology and evaluation of pain and changes in ambulation and gait. Results: Contiguous lesions along the right and left SIJs were achieved in all animals. In one out of three animals, excessive heating of the muscle and skin tissue in the near-field resulted in unwanted muscle necrosis. No changes in animal behavior, ambulation or gait were detected. Conclusions: The initial experiments with MRgHIFU ablation of SIJs in sub-acute swine model show promise for this ablation modality as a non invasive and more precise alternative to the currently used fluoroscopically - guided RF ablations and injections. © 2017 The Author(s). |
| Keywords: | mri; neurolysis; nerve; ablation; focused ultrasound; sacroiliac joint; back pain; denervation; fus; hifu; mrghifu |
| Journal Title: | Journal of Therapeutic Ultrasound |
| Volume: | 5 |
| ISSN: | 2050-5736 |
| Publisher: | Biomed Central Ltd |
| Date Published: | 2017-06-26 |
| Start Page: | 17 |
| Language: | English |
| DOI: | 10.1186/s40349-017-0095-x |
| PROVIDER: | scopus |
| PMCID: | PMC5483839 |
| PUBMED: | 28652915 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 2 August 2017 -- Source: Scopus |
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