Genomic studies indicate a novel combination therapy for follicular lymphoma Journal Article

   


Authors: Oricchio, E.; Wendel, H. G.
Article Title: Genomic studies indicate a novel combination therapy for follicular lymphoma
Abstract: Follicular lymphoma (FL) is an incurable form of B-cell lymphoma. Genomic alterations that inactivate RB signaling are surprisingly common in indolent FL. We show that FLs that are positive for phosphorylated RB respond to dual CDK4/BCL2 inhibition. Our results imply that RB phosphorylation identifies patients likely to benefit from such dual intervention. © 2016 Taylor & Francis Group, LLC.
Keywords: cell cycle; bcl2; follicular lymphoma; therapy
Journal Title: Molecular and Cellular Oncology
Volume: 8
Issue: 6
ISSN: 2372-3556
Publisher: Taylor & Francis Group  
Date Published: 2021-01-01
Start Page: e969640
Language: English
DOI: 10.4161/23723548.2014.969640
PROVIDER: scopus
PMCID: PMC8997257
PUBMED: 35419485
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055145428&doi=10.4161%2f23723548.2014.969640&partnerID=40&md5=abcd6112be6bb4925304b72ada541c9f
Notes: Note -- Export Date: 1 March 2022 -- Source: Scopus
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MSK Authors
  1. Elisa Oricchio
    12 Oricchio
  2. Hans Guido Wendel
    102 Wendel
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