Viral cytotoxic T lymphocytes (CTLs): From bench to bedside Journal Article
| Authors: | Prockop, S. E.; Shahid, S. |
| Article Title: | Viral cytotoxic T lymphocytes (CTLs): From bench to bedside |
| Abstract: | It was first demonstrated almost three decades ago that adoptive transfer of viral-specific T cells could prevent or eradicate viral disease in immune-compromised recipients of allogeneic hematopoetic stem cell transplant (HCT). Since then, advances in our understanding of cellular therapy products as well as in production methods have led to progress in this field now on the brink of having FDA-approved products available for treatment of patients in need. This chapter will highlight some of those advances, as well as the clinical experience to date in the use of these products. © 2022, Springer Nature Switzerland AG. |
| Keywords: | gvhd; adenovirus; mhc; hla; cmv; ebv; hhv6; bk; cmvpp65; latent membrane protein (lmp); ptld; viral cytotoxic t lymphocytes (ctls); viral-specific t cells |
| Journal Title: | Cancer Drug Discovery and Development |
| ISSN: | 2196-9906 |
| Publisher: | Humana Press Inc |
| Date Published: | 2022-01-01 |
| Start Page: | 269 |
| End Page: | 290 |
| Language: | English |
| DOI: | 10.1007/978-3-030-87849-8_15 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Chapter in "Gene and Cellular Immunotherapy for Cancer" (ISBN: 978-3-030-87848-1) -- Export Date: 1 February 2022 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work