CTLA-4 and PD-1 pathway blockade: Combinations in the clinic Journal Article

   


Authors: Callahan, M. K.; Postow, M. A.; Wolchok, J. D.
Article Title: CTLA-4 and PD-1 pathway blockade: Combinations in the clinic
Abstract: Checkpoint blocking antibodies targeting regulatory molecules on T cells such as CTLA-4 and PD-1 have reinvigorated the field of cancer immunotherapy. These agents have demonstrated clinical activity across a variety of tumor types. Now that safety and clinical activity has been demonstrated in the monotherapy setting, the field is moving in the direction of testing novel combinations. Copyright © 2015 Callahan, Postow and Wolchok.
Keywords: ipilimumab; immunotherapy; pd-1; nivolumab; clta-4
Journal Title: Frontiers in Oncology
Volume: 4
ISSN: 2234-943X
Publisher: Frontiers Media S.A.  
Date Published: 2015-01-15
Start Page: 385
Language: English
DOI: 10.3389/fonc.2014.00385
PROVIDER: scopus
PMCID: PMC4295550
PUBMED: 25642417
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85119037788&doi=10.3389%2ffonc.2014.00385&partnerID=40&md5=3be49b715761f55a11ba638809a09261
Notes: Review -- Export Date: 1 December 2021 -- Source: Scopus
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. Jedd D Wolchok
    905 Wolchok
  2. Michael Andrew Postow
    361 Postow
  3. Margaret Kathleen Callahan
    197 Callahan
Related MSK Work