Increase in the efficiency of plateletpheresis Journal Article


Authors: Reich, L. M.; Miller, J.; Ellis, S.; Mayer, K.
Article Title: Increase in the efficiency of plateletpheresis
Abstract: Transfusion of large amounts of platelets from a single donor instead of multiple donors reduces the patient's exposure to infection and diverse antigens. Gmur et al. documented evidence supporting the delay of onset of refractoriness to platelet transfusion as well as a diminution in demonstrable alloantibodies in patients receiving single donor platelets versus those who were transfused random pooled platelets1. The patient who is refractory to platelet transfusions may also do better from selectively matched single donors. If we are able to maximize the yield in the shortest possible time, we would also improve the efficiency and productivity of the blood bank and make the procedure more convenient for the donor. We developed a new set of operating parameters to be used with a new component plate for the Fenwal CS 3000(TM). This new plate was redesigned by the manufacturer. By using the new parameters, we were able to obtain a sufficient number of platelets in the shortest period of time with the least contamination with lymphocytes.
Keywords: human cell; methodology; lymphatic system; lymphocyte; cell separation; therapy; human; thrombocytopheresis; blood and hemopoietic system
Journal Title: Plasma Therapy and Transfusion Technology
Volume: 6
Issue: 3
ISSN: 0278-6222
Publisher: Elsevier, Inc.  
Date Published: 1985-01-01
Start Page: 409
End Page: 414
Language: English
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus