Neuronal antinuclear antibody in sensory neuronopathy from lung cancer Journal Article


Authors: Graus, F.; Cordon-Cardo, C.; Posner, J. B.
Article Title: Neuronal antinuclear antibody in sensory neuronopathy from lung cancer
Abstract: We found an antinuclear antibody highly restricted to nuclei of neurons in two patients with subacute sensory neuronopathy complicating oat cell carcinoma of the lung. Serum was tested by indirect immunofluorescence and immunoperoxidase staining. At low concentrations of antibody, only the nuclei of the neurons were stained. At high concentrations, there was also staining of the nuclei of glial cells and fetal nonneural tissues. The cytoplasm of most neurons was stained with the immunoperoxidase method. © 1985 American Academy of Neurology.
Keywords: case report; sensory neuropathy; lung neoplasms; lung cancer; neurons; immunofluorescence; antigens; diagnosis; glia cell; antinuclear antibody; nerve cell; serum; peripheral nervous system diseases; peripheral nervous system; carcinoma, small cell; nervous system; middle age; respiratory system; sensation; human; female; priority journal; antibodies, antinuclear; oat cell carcinoma
Journal Title: Neurology
Volume: 35
Issue: 4
ISSN: 0028-3878
Publisher: Lippincott Williams & Wilkins  
Date Published: 1985-04-01
Start Page: 538
End Page: 543
Language: English
DOI: 10.1212/wnl.35.4.538
PROVIDER: scopus
PUBMED: 2984600
DOI/URL:
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Jerome B Posner
    211 Posner