The natural history of lumbosacral plexopathy in cancer Journal Article


Authors: Jaeckle, K. A.; Young, D. F.; Foley, K. M.
Article Title: The natural history of lumbosacral plexopathy in cancer
Abstract: We studied 85 cancer patients with lumbosacral plexopathy and documented pelvic tumor by CT or biopsy. Three clinical syndromes were delineated: lower (L4-S1), 51%; upper (L1-L4), 31%; and pan-plexopathy (L1-S3), 18%. Seventy percent of patients had the insidious onset of pelvic or radicular leg pain, followed weeks to months later by sensory symptoms and weakness. The quintet of leg pain, weakness, edema, rectal mass, and hydronephrosis suggests plexopathy due to cancer. CT showed pelvic tumor in 96%. On myelography, epidural extension, usually below the conus medullaris, was seen in 45%. With treatment, only 28% of patients had objective responses on CT and 17% on examination. © 1985 American Academy of Neurology.
Keywords: case report; neoplasms; computer assisted tomography; central nervous system; gastrointestinal neoplasms; diagnosis; pelvis tumor; pelvic neoplasms; bone; electromyography; peripheral nervous system diseases; peripheral nervous system; leg; muscle; computer analysis; middle age; lumbosacral plexus; myelography; neuromuscular diseases; human; male; female; priority journal; plexus lesion
Journal Title: Neurology
Volume: 35
Issue: 1
ISSN: 0028-3878
Publisher: Lippincott Williams & Wilkins  
Date Published: 1985-01-01
Start Page: 8
End Page: 15
Language: English
DOI: 10.1212/wnl.35.1.8
PROVIDER: scopus
PUBMED: 2981417
DOI/URL:
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus
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  1. Kathleen M Foley
    199 Foley