Growth of human bone marrow in vitro Journal Article
| Authors: | Svet-Moldavsky, I.; Gulati, S. C.; Clarkson, B. |
| Article Title: | Growth of human bone marrow in vitro |
| Abstract: | Attempts were made to establish human bone marrow (HBM) culture. Cell proliferation was triggered by medium conditioned by acute myelocytic leukemic (AML) cells exposed to 12-O-tetradecanoyl-phorbol-13-acetate (TPA). A 6-15 fold multiplication of myelomonocytic cells was obtained in tissue culture from HBM cells. Proliferation of granulocyte-macrophage colony forming cells (CFC-GM) occurred up to 30-fold. The morphology of the cells and cytochemical markers were investigated at all stages of the culture. © 1985. |
| Keywords: | acute granulocytic leukemia; pathophysiology; cytology; bone marrow cells; cells, cultured; cell division; culture medium; drug effect; pathology; cell culture; hematopoiesis; bone marrow cell; monocyte; monocytes; macrophage; macrophages; colony-stimulating factors; culture media; phorbol 13 acetate 12 myristate; tetradecanoylphorbol acetate; colony stimulating factor; leukemia, myelocytic, acute; human; article; colony stimulating factors; phorbol derivative; phorbols |
| Journal Title: | Cell Biology International Reports |
| Volume: | 9 |
| Issue: | 9 |
| ISSN: | 0309-1651 |
| Publisher: | Elsevier B.V. |
| Date Published: | 1985-09-01 |
| Start Page: | 833 |
| End Page: | 840 |
| Language: | English |
| DOI: | 10.1016/0309-1651(85)90102-x |
| PUBMED: | 3876165 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 26 October 2021 -- Source: Scopus |
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