Epidermoid cancer of the anal margin. Pathologic features, treatment, and clinical results Journal Article


Authors: Greenall, M. J.; Quan, S. H. Q.; Stearns, M. W.; Urmacher, C.; DeCosse, J. J.
Article Title: Epidermoid cancer of the anal margin. Pathologic features, treatment, and clinical results
Abstract: Epidermoid cancer of the anal margin should be distinguished from that in the canal because of its different clinical and pathologic characteristics, the suitability of local excision for its treatment, and its better overall prognosis. In addition, margin cancer rarely metastasises to visceral sites. Forty-eight patients with epidermoid cancer of the anal margin were reviewed. Two refused treatment, 4 had palliative therapy for advanced, inoperable disease, 31 had local excision, and 11 were treated by abdominoperineal resection. Local excision provided satisfactory results with a corrected 5 year survival of 88 percent, although locoregional recurrence developed in 46 percent of these patients during follow-up. A second local excision or inguinal lymphadenectomy provided good results in the patients with recurrence. Abdominoperineal resection did not provide better overall survival figures. © 1985 Technical Publishing, All right reserved.
Keywords: adult; clinical article; aged; middle aged; squamous cell carcinoma; carcinoma, squamous cell; follow-up studies; neoplasm recurrence, local; palliative therapy; reoperation; neoplasm metastasis; anus cancer; methods; therapy; rectum abdominoperineal resection; anus neoplasms; large intestine; humans; prognosis; human; male; female; priority journal
Journal Title: American Journal of Surgery
Volume: 149
Issue: 1
ISSN: 0002-9610
Publisher: Elsevier Inc.  
Date Published: 1985-01-01
Start Page: 95
End Page: 101
Language: English
DOI: 10.1016/s0002-9610(85)80016-7
PROVIDER: scopus
PUBMED: 3966647
DOI/URL:
Notes: Article -- Export Date: 26 October 2021 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Stuart H. Q. Quan
    28 Quan
  2. Jerome J. DeCosse
    25 DeCosse