Authors: | Zavaleta, C. L.; Kircher, M. F.; Gambhir, S. S. |
Article Title: | Raman's "effect" on molecular imaging |
Abstract: | Raman spectroscopy is an optical technique that offers unsurpassed sensitivity and multiplexing capabilities to the field of molecular imaging. In the past, Raman spectroscopy had predominantly been used as an analytic tool for routine chemical analysis, but more recently, researchers have been able to harness its unique properties for imaging and spectral analysis of molecular interactions in cell populations and preclinical animal models. Additionally, researchers have already begun to translate this optical technique into a novel clinical diagnostic tool using various endoscopic strategies. Copyright © 2011 by the Society of Nuclear Medicine, Inc. |
Keywords: | protein expression; review; nonhuman; cancer grading; diagnostic accuracy; sensitivity and specificity; animals; breast cancer; image analysis; skin cancer; cell differentiation; molecular imaging; cell type; image quality; cancer cell; cellular distribution; stomach cancer; nanoparticle; cell aggregation; esophagus cancer; tumor classification; spectroscopy; ligand binding; cells; raman spectrometry; spectrum analysis, raman; raman's effect; nanorod |
Journal Title: | Journal of Nuclear Medicine |
Volume: | 52 |
Issue: | 12 |
ISSN: | 0161-5505 |
Publisher: | Society of Nuclear Medicine |
Date Published: | 2011-12-01 |
Start Page: | 1839 |
End Page: | 1844 |
Language: | English |
DOI: | 10.2967/jnumed.111.087775 |
PROVIDER: | scopus |
PUBMED: | 21868625 |
DOI/URL: | |
Notes: | --- - "Export Date: 1 February 2012" - "CODEN: JNMEA" - "Source: Scopus" |