Staging, recurrence and follow-up of uterine cervical cancer using MRI: Updated Guidelines of the European Society of Urogenital Radiology after revised FIGO staging 2018 Guidelines


Authors: Manganaro, L.; Lakhman, Y.; Bharwani, N.; Gui, B.; Gigli, S.; Vinci, V.; Rizzo, S.; Kido, A.; Cunha, T. M.; Sala, E.; Rockall, A.; Forstner, R.; Nougaret, S.
Title: Staging, recurrence and follow-up of uterine cervical cancer using MRI: Updated Guidelines of the European Society of Urogenital Radiology after revised FIGO staging 2018
Abstract: Objectives: The recommendations cover indications for MRI examination including acquisition planes, patient preparation, imaging protocol including multi-parametric approaches such as diffusion-weighted imaging (DWI-MR), dynamic contrast-enhanced imaging (DCE-MR) and standardised reporting. The document also underscores the value of whole-body 18-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (FDG-PET/CT) and highlights potential future methods. Methods: In 2019, the ESUR female pelvic imaging working group reviewed the revised 2018 FIGO staging system, the up-to-date clinical management guidelines, and the recent imaging literature. The RAND-UCLA Appropriateness Method (RAM) was followed to develop the current ESUR consensus guidelines following methodological steps: literature research, questionnaire developments, panel selection, survey, data extraction and analysis. Results: The updated ESUR guidelines are recommendations based on ≥ 80% consensus among experts. If ≥ 80% agreement was not reached, the action was indicated as optional. Conclusions: The present ESUR guidelines focus on the main role of MRI in the initial staging, response monitoring and evaluation of disease recurrence. Whole-body FDG-PET plays an important role in the detection of lymph nodes (LNs) and distant metastases. Key Points: • T2WI and DWI-MR are now recommended for initial staging, monitoring of response and evaluation of recurrence. • DCE-MR is optional; its primary role remains in the research setting. • T2WI, DWI-MRI and whole-body FDG-PET/CT enable comprehensive assessment of treatment response and recurrence © 2020, European Society of Radiology.
Keywords: magnetic resonance imaging; neoplasm staging; neoplasm recurrence; uterine cervical neoplasms; diffusion weighted imaging
Journal Title: European Radiology
Volume: 31
Issue: 10
ISSN: 0938-7994
Publisher: Springer  
Date Published: 2021-10-01
Start Page: 7802
End Page: 7816
Language: English
DOI: 10.1007/s00330-020-07632-9
PUBMED: 33852049
PROVIDER: scopus
DOI/URL:
Notes: Article -- Erratum issued, see DOI: 10.1007/s00330-021-08066-7 -- Export Date: 1 October 2021 -- Source: Scopus
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  1. Yuliya Lakhman
    95 Lakhman