Authors: | Kantarjian, H. M.; Short, N. J.; Fathi, A. T.; Marcucci, G.; Ravandi, F.; Tallman, M.; Wang, E. S.; Wei, A. H. |
Review Title: | Acute myeloid leukemia: Historical perspective and progress in research and therapy over 5 decades |
Abstract: | With the Food and Drug Administration approval of 9 agents for different acute myeloid leukemia (AML) indications, the prognosis and management of AML is evolving rapidly. Herein, we review the important milestones in the history of AML research and therapy, discuss insights regarding prognostic assessment and prediction of treatment outcome, detail practical supportive care measures, and summarize the current treatment landscape and areas of evolving research. © 2021 Elsevier Ltd |
Keywords: | biology; targeted therapy; therapy; aml; prognosis |
Journal Title: | Clinical Lymphoma, Myeloma and Leukemia |
Volume: | 21 |
Issue: | 9 |
ISSN: | 2152-2650 |
Publisher: | Elsevier Inc. |
Date Published: | 2021-09-01 |
Start Page: | 580 |
End Page: | 597 |
Language: | English |
DOI: | 10.1016/j.clml.2021.05.016 |
PUBMED: | 34176779 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | Review -- Export Date: 1 October 2021 -- Source: Scopus |