Restorative oncodermatology: Diagnosis and management of dermatologic sequelae from cancer therapies Review


Authors: Rossi, A. M.; Hibler, B. P.; Navarrete-Dechent, C.; Lacouture, M. E.
Review Title: Restorative oncodermatology: Diagnosis and management of dermatologic sequelae from cancer therapies
Abstract: The long-term survival of patients with cancer has risen dramatically during the last few decades. Despite this remarkable success, the same treatments that have enabled cure or remission often secondarily affect the skin, hair, and nails. Conditions including scarring, striae distensae, persistent alopecia, pigmentary changes, nail alterations, chronic radiation dermatitis, and radiation fibrosis have been associated with anxiety, depression, decreased quality of life, and impaired function. These dermatologic changes are cosmetically disfiguring, may limit activities, and are a visual reminder of past illness. Interventions toward improving these untoward sequelae and restoring the appearance and function of skin and appendages are critical for normalization and may contribute to improved quality of life in cancer survivors. Here, we outline dermatologic sequelae of cancer therapies with a review of medical and procedural treatment strategies to restore dermatologic health in the survivorship population.
Keywords: chemotherapy; quality of life; radiation; lymphedema; hyperpigmentation; surgery; alopecia; reconstruction; long-term survivors; scar; hypopigmentation; breast-cancer; quality-of-life; cancer survivors; telangiectasias; induced alopecia; pulsed dye-laser; cancer; striae; dermal fillers; postinflammatory hyperpigmentation; hair removal; neuromodulators; striae-distensae; abdominal striae; scar management
Journal Title: Journal of the American Academy of Dermatology
Volume: 85
Issue: 3
ISSN: 0190-9622
Publisher: Mosby Elsevier  
Date Published: 2021-09-01
Start Page: 693
End Page: 707
Language: English
ACCESSION: WOS:000683573600022
DOI: 10.1016/j.jaad.2020.08.005
PROVIDER: wos
PMCID: PMC7868476
PUBMED: 32781177
Notes: Review -- Source: Wos
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MSK Authors
  1. Mario E Lacouture
    457 Lacouture
  2. Anthony Rossi
    236 Rossi
  3. Brian Phillip Hibler
    55 Hibler