Dermoscopic features of basal cell carcinoma and its subtypes: A systematic review Review
| Authors: | Reiter, O.; Mimouni, I.; Dusza, S.; Halpern, A. C.; Leshem, Y. A.; Marghoob, A. A. |
| Review Title: | Dermoscopic features of basal cell carcinoma and its subtypes: A systematic review |
| Abstract: | Background: Multiple studies have reported on dermoscopic structures in basal cell carcinoma (BCC) and its subtypes, with varying results. Objective: To systematically review the prevalence of dermoscopic structures in BCC and its subtypes. Methods: Databases and reference lists were searched for relevant trials according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Studies were assessed for the relative proportion of BCC dermoscopic features. Random-effects models were used to estimate summary effect sizes. Results: Included were 31 studies consisting of 5950 BCCs. The most common dermoscopic features seen in BCC were arborizing vessels (59%), shiny white structures (49%), and large blue-grey ovoid nests (34%). Arborizing vessels, ulceration, and blue-grey ovoid nests and globules were most common in nodular BCC; short-fine telangiectasia, multiple small erosions, and leaf-like, spoke wheel and concentric structures in superficial BCC; porcelain white areas and arborizing vessels in morpheaform BCC; and arborizing vessels and ulceration in infiltrative BCC. Limitations: Studies had significant heterogeneity. Studies reporting BCC histopathologic subtypes did not provide clinical data on pigmentation of lesions. Conclusion: In addition to arborizing vessels, shiny white structures are a common feature of BCC. A constellation of dermoscopic features may aid in differentiating between BCC histopathologic subtypes. © 2019 American Academy of Dermatology, Inc. |
| Keywords: | dermoscopy; basal cell carcinoma; dermatoscopy; ulceration; bcc; nodular basal cell carcinoma; superficial basal cell carcinoma; infiltrative basal cell carcinoma; pigmented basal cell carcinoma; rosettes; polymorphous vessels; arborizing vessels; blue-white veil; concentric structures; corkscrew vessels; dotted vessels; glomerular vessels; hairpin vessels; large blue-grey ovoid nests; leaf-like areas; morpheaform basal cell carcinoma; multiple blue-grey dots and globules; multiple in-focus dots; multiple small erosions; nonpigmented basal cell carcinoma; shiny white structures; shiny white-red structureless background; short-fine telangiectasia; spoke wheel areas |
| Journal Title: | Journal of the American Academy of Dermatology |
| Volume: | 85 |
| Issue: | 3 |
| ISSN: | 0190-9622 |
| Publisher: | Mosby Elsevier |
| Date Published: | 2021-09-01 |
| Start Page: | 653 |
| End Page: | 664 |
| Language: | English |
| DOI: | 10.1016/j.jaad.2019.11.008 |
| PUBMED: | 31706938 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 September 2021 -- Source: Scopus |
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534Marghoob -
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