Clinical and dermoscopic features of Fibroepithelioma of Pinkus: Case series with an emphasis on hypopigmented to pink lines intersecting at acute angles Journal Article

   

Authors:	Nanda, J. K.; Marghoob, N.; Forero Cuevas, D. M.; Lee, K. R.; Levy, M.; Reiter, O.; Busam, K. J.; Marghoob, A. A.
Article Title:	Clinical and dermoscopic features of Fibroepithelioma of Pinkus: Case series with an emphasis on hypopigmented to pink lines intersecting at acute angles
Abstract:	Fibroepithelioma of Pinkus (FEP) is a subtype of basal cell carcinoma (BCC) that can clinically resemble intradermal nevi (IDN) and fibromas. We performed a retrospective review of consecutively biopsied lesions confirmed to be FEP on histopathology diagnosed from January 1, 2008 to April 8, 2019. Clinical (n = 48), contact non-polarized dermoscopy (NPD) (n = 44), and contact polarized dermoscopy (PD) (n = 22) images from 36 patients were reviewed. Mean age was 64.5 years (SD 15.1 years, range 24–86 years) at diagnosis of first FEP lesion. Most lesions were located on the torso (n = 28, 58.3%), followed by the lower extremity (n = 9, 18.8%). The most common differential diagnoses at the time of biopsy included BCC (n = 40) and nevus (other than IDN, n = 5). Clinically, FEP were pink (95.8%), scaly (66.7%) papules (77.1%) displaying disrupted skin markings (62.5%) and absence of hair follicles (87.5%). NPD revealed serpentine (97.7%), dotted (81.8%), or polymorphous vessels (86.4%), and hypopigmented to pink lines intersecting at acute angles (HPLA) (52.3%). PD demonstrated serpentine (95.5%), dotted (86.4%), or polymorphous vessels (81.8%), shiny white lines (50.0%), and HPLA (59.1%). Classic features of BCC such as arborizing vessels (n = 2), ulceration (n = 1), shiny white blotches and strands (n = 1), blue-gray ovoid nest (n = 1), and leaf-like areas (n = 1) were uncommon. FEP often presents as scaly, erythematous papules with disrupted skin markings and absence of hair follicles. Dermoscopy reveals polymorphous vessels with shiny white lines and HPLA. © 2020, Springer-Verlag GmbH Germany, part of Springer Nature.
Keywords:	dermoscopy; basal cell carcinoma; fibroepithelioma of pinkus; polymorphous vessels; shiny white lines
Journal Title:	Archives of Dermatological Research
Volume:	313
Issue:	8
ISSN:	0340-3696
Publisher:	Springer
Date Published:	2021-10-01
Start Page:	633
End Page:	640
Language:	English
DOI:	10.1007/s00403-020-02142-6
PUBMED:	32978676
PROVIDER:	scopus
PMCID:	PMC9396668
DOI/URL:	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85091429693&doi=10.1007%2fs00403-020-02142-6&partnerID=40&md5=aa8e63693bb5981ef8821b4efe984644
Notes:	Article -- Export Date: 1 September 2021 -- Source: Scopus

https://synapse.mskcc.org/synapse/works/has_related_data_chk/186106