Two-year quality of life outcomes after robotic-assisted minimally invasive and open esophagectomy Journal Article
| Authors: | Vimolratana, M.; Sarkaria, I. S.; Goldman, D. A.; Rizk, N. P.; Tan, K. S.; Bains, M. S.; Adusumilli, P. S.; Sihag, S.; Isbell, J. M.; Huang, J.; Park, B. J.; Molena, D.; Rusch, V. W.; Jones, D. R.; Bott, M. J. |
| Article Title: | Two-year quality of life outcomes after robotic-assisted minimally invasive and open esophagectomy |
| Abstract: | Background: Robotic-assisted minimally invasive esophagectomy (RAMIE) is a safe alternative to open esophagectomy (OE). However, differences in quality of life (QOL) after these procedures remain unclear. We previously reported short-term QOL outcomes after RAMIE and OE and describe here our results from 2 years of follow-up. Methods: We conducted a prospective, nonrandomized trial of patients with esophageal cancer undergoing transthoracic resection by RAMIE or OE at a single institution. The primary outcomes were patient-reported QOL, measured by the Functional Assessment of Cancer Therapy–Esophageal (FACT-E), and pain, measured by the Brief Pain Inventory (BPI). Generalized linear models were used to assess the relationship between QOL outcomes and surgery cohort. P values were adjusted (P-adj) within each model using the false discovery rate correction. Results: Esophagectomy was performed in 170 patients (106 OE and 64 RAMIE). The groups did not differ significantly by any measured clinicopathologic variables. After covariates were controlled for, FACT-E scores were higher in the RAMIE cohort than in the OE cohort (parameter estimate [PE], 6.13; P-adj = .051). RAMIE was associated with higher esophageal cancer subscale (PE, 2.72; P-adj = .022) and emotional well-being (PE, 1.25; P-adj = .016) scores. BPI pain severity scores were lower in the RAMIE cohort than in the OE cohort (PE, −0.56; P-adj = .005), but pain interference scores did not differ significantly between groups (P-adj = .11). Conclusions: During 2 years of follow-up, RAMIE was associated with improved patient-reported QOL, including esophageal symptoms, emotional well-being, and decreased pain, compared with OE. © 2021 The Society of Thoracic Surgeons |
| Journal Title: | Annals of Thoracic Surgery |
| Volume: | 112 |
| Issue: | 3 |
| ISSN: | 0003-4975 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2021-09-01 |
| Start Page: | 880 |
| End Page: | 889 |
| Language: | English |
| DOI: | 10.1016/j.athoracsur.2020.09.027 |
| PUBMED: | 33157056 |
| PROVIDER: | scopus |
| PMCID: | PMC9425152 |
| DOI/URL: | |
| Notes: | Conference Paper -- Export Date: 1 September 2021 -- Source: Scopus |
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