L-phenylalanine mustard-dianhydrogalactitol and hyponatremia Journal Article
| Authors: | Helson, L.; Sadof, M. D.; Wernovsky, G.; Gulati, S. |
| Article Title: | L-phenylalanine mustard-dianhydrogalactitol and hyponatremia |
| Abstract: | The incidence of hyponatremia in 34 patients following administration of high-dose L-phenylalanine mustard (L-PAM) and dianhydrogalactitol (DAG) was determined. Two consecutive daily levels of 133 mEq/l or less were observed in 12 patients. These episodes coincided with the advent of diarrhea about 10-12 days after drug administration. The hyponatremia was not due to the syndrome of inappropriate antidiuretic hormone secretion. © 1986 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. |
| Keywords: | clinical article; case report; cancer combination chemotherapy; diarrhea; prospective studies; diagnosis, differential; cyclophosphamide; melphalan; vincristine; gastrointestinal toxicity; hyponatremia; neuroblastoma; drug therapy; neuroectoderm tumor; inappropriate adh syndrome; adverse drug reaction; therapy; intravenous drug administration; nervous system neoplasms; intoxication; human; dianhydrogalactitol; inappropriate antidiuretic hormone secretion; l-phenylalanine mustard |
| Journal Title: | Pediatric Hematology and Oncology |
| Volume: | 3 |
| Issue: | 3 |
| ISSN: | 0888-0018 |
| Publisher: | Taylor & Francis Group |
| Date Published: | 1986-01-01 |
| Start Page: | 287 |
| End Page: | 291 |
| Language: | English |
| DOI: | 10.3109/08880018609031229 |
| PUBMED: | 3153241 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 18 August 2021 -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work