Tardive dyskinesia associated with high-dose intravenous metoclopramide - To the editor Journal Article


Author: Breitbart, W.
Article Title: Tardive dyskinesia associated with high-dose intravenous metoclopramide - To the editor
Abstract: To the Editor: A 45-year-old white man with recurrent testicular cancer underwent six courses of chemotherapy with cisplatin and etoposide during an eight-month period. During each five-day course, metoclopramide (in high intravenous doses of 2 mg per kilogram of body weight) was used as an antiemetic. The metoclopramide was usually first given 30 minutes before chemotherapy and then as needed. The patient received the following total intravenous doses: 1800 mg in course 1, 430 mg in course 2, 685 mg in course 3, 685 mg in course 4, 1080 mg in course 5, and 560 mg in course 6. He. © 1986, Massachusetts Medical Society. All rights reserved.
Keywords: adult; case report; cisplatin; neurotoxicity; letter; ovarian neoplasms; etoposide; central nervous system; testicular neoplasms; antiemetic agent; drug dose; drug therapy; testis cancer; metoclopramide; adverse drug reaction; therapy; intravenous drug administration; injections, intravenous; nervous system; middle age; intoxication; diazepam; cholinergic receptor blocking agent; male genital system; tardive dyskinesia; dyskinesia, drug-induced; human; male; female; priority journal
Journal Title: New England Journal of Medicine
Volume: 315
Issue: 8
ISSN: 0028-4793
Publisher: Massachusetts Medical Society  
Date Published: 1986-08-21
Start Page: 518
Language: English
DOI: 10.1056/nejm198608213150816
PUBMED: 3736635
PROVIDER: scopus
DOI/URL:
Notes: Letter -- Export Date: 18 August 2021 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. William S Breitbart
    504 Breitbart