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To the Editor: In their recent review of treatment results in osteosarcoma, Goorin et al.1 stated that the disease-free and overall survival rates among patients treated by segmental limb resection have not been significantly different from those among patients who underwent amputation. This, however, has not been true in the German–Austrian osteosarcoma trials. In our report on the Cooperative Osteosarcoma Study (COSS 80),2 cited by Goorin et al., we pointed out that, although local recurrences were not a serious problem after limb-salvage surgery, the incidence of pulmonary metastases was remarkably higher than after amputation. In a recently completed Cox regression. © 1986, Massachusetts Medical Society. All rights reserved. |