Use of an IgA-depleted intravenous immunoglobulin in a patient with an anti-IgA antibody Journal Article
| Authors: | Cunningham-Rundles, C.; Wong, S.; Bjorkander, J.; Hanson, L. A. |
| Article Title: | Use of an IgA-depleted intravenous immunoglobulin in a patient with an anti-IgA antibody |
| Abstract: | In this report we describe the use of an IgA-depleted preparation of intravenous γ-globulin in a patient with hypogammaglobulinemia and an anti-IgA antibody. An IgA containing intravenous γ-globulin had previously produced anaphylactoid reactions, immune complex formation, and complement activation. The patient has had no reactions to the IgA-depleted preparation after 18 months of treatment; immune complex formation and complement activation have not been demonstrated, and the titer of antibody to IgA has diminished. © 1986. |
| Keywords: | unclassified drug; case report; immunoglobulin; immunoglobulin g; enzyme-linked immunosorbent assay; drug therapy; anaphylaxis; therapy; intravenous drug administration; immunoglobulins, intravenous; immunoglobulin a; middle age; antigen antibody complex; antibodies, anti-idiotypic; antigen-antibody complex; complement activation; hypogammaglobulinemia; human; female; priority journal; agammaglobulinemia; support, non-u.s. gov't; support, u.s. gov't, p.h.s.; immunoglobulin a, secretory; blood and hemopoietic system; iga deficiency; gammastan |
| Journal Title: | Clinical Immunology and Immunopathology |
| Volume: | 38 |
| Issue: | 2 |
| ISSN: | 0090-1229 |
| Publisher: | Elsevier Inc. |
| Date Published: | 1986-02-01 |
| Start Page: | 141 |
| End Page: | 149 |
| Language: | English |
| DOI: | 10.1016/0090-1229(86)90133-9 |
| PUBMED: | 3079685 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Article -- Export Date: 18 August 2021 -- Source: Scopus |
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