The role of external beam in brachytherapy Journal Article
| Authors: | Zaider, M.; Zelefsky, M. J.; Cohen, G. N.; Chui, C. S.; Yorke, E. D.; Hunt, M. A.; Happersett, L. |
| Article Title: | The role of external beam in brachytherapy |
| Abstract: | In this paper we put forward the claim that the combination of low dose-rate brachytherapy (BRT) and fractionated external-beam radiotherapy (EBRT) may, when planned to take advantage of the relative advantages of each of these two modalities, result in enhanced tumor dose with no penalties to organs at risk. The concept of iso-effective dose (IED) serves the role of common currency for fusing BRT and EBRT and, for evaluation purposes, converting back the resulting IED distribution into a biologically equivalent plan delivered by any single modality. It we accept this view, there are further questions that must be answered regarding practical matters. We show how to deal with these questions by describing an actual patient plan. © 2007 Future Medicine Ltd. |
| Keywords: | intensity modulated radiation therapy; treatment planning; radiation dose; combined modality therapy; neoplasms; dosimetry; radiation dose fractionation; brachytherapy; malignant neoplastic disease; radiation hazard; radiotherapy planning, computer-assisted; relative biological effectiveness; external beam radiotherapy; dose fractionation; radiation dose distribution; calculation; external-beam radiotherapy; tumor-control probability; biologically-effective dose; isoeffective dose; synergistic effect of radiations |
| Journal Title: | Future Oncology |
| Volume: | 3 |
| Issue: | 2 |
| ISSN: | 1479-6694 |
| Publisher: | Future Medicine |
| Date Published: | 2007-04-01 |
| Start Page: | 159 |
| End Page: | 168 |
| Language: | English |
| DOI: | 10.2217/14796694.3.2.159 |
| PUBMED: | 17381416 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 2" - "Export Date: 17 November 2011" - "Source: Scopus" |
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