Scleral hyperplasia induced by heat Journal Article

  


Authors: Finger, P. T.; Curtin, B. J.; Packer, S.; Svitra, P. P.; Iwamoto, T.; Whitmore, W. G.; Jakobiec, F. A.
Article Title: Scleral hyperplasia induced by heat
Abstract: We evaluated low-level heating as a stimulus to induce hyperplasia of normal rabbit sclera. Heat treatments were administered by placing an etched-element heater on bare sclera. Contact thermotherapy with a conductive device provided a favorable dose distribution for local scleral heating. A purely conductive heat source was selected to minimize intraocular heat penetration and to determine whether the scleral reaction was a primary thermal effect. Histologic examination of treated specimens showed thickening of normal rabbit sclera with preservation of the underlying normal ocular structures. Electron microscopic examination of treated sclera showed newly formed collagen fibrils adjacent to sclerocytes. These fibroblasts were activated, as manifested by well-developed rough-surfaced endoplasmic reticulum and hypertrophic Golgi complexes. © 1986.
Keywords: nonhuman; electron microscopy; animals; animal experiment; histology; hyperplasia; sclera; ultrastructure; eye diseases; rabbits; heating; rabbit; heat; visual system; priority journal; thermal radiation
Journal Title: American Journal of Ophthalmology
Volume: 102
Issue: 1
ISSN: 0002-9394
Publisher: Elsevier Science, Inc.  
Date Published: 1986-07-01
Start Page: 25
End Page: 32
Language: English
DOI: 10.1016/0002-9394(86)90204-7
PUBMED: 3728621
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022522098&doi=10.1016%2f0002-9394%2886%2990204-7&partnerID=40&md5=0dedb643197ac99eee12ac330c7e67b5
Notes: Article -- Export Date: 18 August 2021 -- Source: Scopus
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