Steroid-related development of Kaposi's sarcoma in a homosexual man with Burkitt's lymphoma Journal Article

  


Authors: Real, F. X.; Krown, S. E.; Koziner, B.
Article Title: Steroid-related development of Kaposi's sarcoma in a homosexual man with Burkitt's lymphoma
Abstract: The development of Kaposi's sarcoma has been associated with either iatrogenic or disease-related immunodeficiency. This report describes a homosexual man who presented with Burkitt's lymphoma and later had pneumonitis, which was treated with a high dose of corticosteroids. Kaposi's sarcoma subsequently developed, and regressed completely when the chemotherapy and corticosteroid therapy were withdrawn. The evidence from the literature relating corticosteroid therapy to the development of Kaposi's sarcoma is discussed, as well as the possible multifactorial origin of the immunodeficiency in which setting this tumor occurs. The observations in this patient suggest that corticosteroids should be used with extreme caution in patients with acquired immunodeficiency and those at risk for its development. © 1986.
Keywords: adult; prednisone; case report; doxorubicin; cytarabine; antineoplastic combined chemotherapy protocols; cyclophosphamide; vincristine; risk; pneumonia; lymphatic system; asparaginase; homosexuality; acquired immune deficiency syndrome; acquired immunodeficiency syndrome; kaposi sarcoma; sarcoma, kaposi; immune deficiency; corticosteroid; drug therapy; immunosuppressive treatment; adverse drug reaction; therapy; burkitt lymphoma; tioguanine; oral drug administration; reticuloendothelial system; chemical carcinogenesis; human; male; priority journal; support, non-u.s. gov't; support, u.s. gov't, p.h.s.
Journal Title: The American Journal of Medicine
Volume: 80
Issue: 1
ISSN: 0002-9343
Publisher: Elsevier Inc.  
Date Published: 1986-01-01
Start Page: 119
End Page: 122
Language: English
DOI: 10.1016/0002-9343(86)90060-4
PUBMED: 3942143
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022646214&doi=10.1016%2f0002-9343%2886%2990060-4&partnerID=40&md5=f6fcdd4ef7b8347db979369c1eb1218d
Notes: Article -- Export Date: 18 August 2021 -- Source: Scopus
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MSK Authors
  1. Susan Krown
    156 Krown
  2. Francisco X. Real
    42 Real
  3. Benjamin Koziner
    52 Koziner
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