The management of pancreatic cancer. Current expert opinion and recommendations derived from the 8th World Congress on Gastrointestinal Cancer, Barcelona, 2006 Journal Article
| Authors: | Verslype, C.; Van Cutsem, E.; Dicato, M.; Cascinu, S.; Cunningham, D.; Díaz-Rubio, E.; Glimelius, B.; Haller, D.; Haustermans, K.; Heinemann, V.; Hoff, P.; Johnston, P. G.; Kerr, D.; Labianca, R.; Louvet, C.; Minsky, B.; Moore, M.; Nordlinger, B.; Pedrazzoli, S.; Roth, A.; Rothenberg, M.; Rougier, P.; Schmoll, H. J.; Tabernero, J.; Tempero, M.; van de Velde, C.; Van Laethem, J. L.; Zalcberg, J. |
| Article Title: | The management of pancreatic cancer. Current expert opinion and recommendations derived from the 8th World Congress on Gastrointestinal Cancer, Barcelona, 2006 |
| Abstract: | This article summarizes the expert discussion on the management of pancreatic cancer, which took place during the 8th World Congress on Gastrointestinal Cancer in June 2006 in Barcelona. A multidisciplinary approach to a patient with pancreatic cancer is essential, in order to guarantee an optimal staging, surgery, selection of the appropriate (neo-)adjuvant strategy and chemotherapeutic choice management. Moreover, optimal symptomatic management requires a dedicated team of health care professionals. Quality control of surgery and pathology is especially important in this disease with a high locoregional failure rate. There is now solid evidence in favour of chemotherapy in both the adjuvant and palliative setting, and gemcitabine combined with erlotinib, capecitabine or platinum compounds seems to be slightly more active than gemcitabine alone in advanced pancreatic cancer. There is a place for chemoradiotherapy in selected patients with locally advanced disease, while the role in the adjuvant setting remains controversial. Those involved in the care for patients with pancreatic cancer should be encouraged to participate in well-designed clinical trials, in order to increase the evidence-based knowledge and to make further progress. © 2007 European Society for Medical Oncology. |
| Keywords: | cancer survival; clinical trial; histopathology; bevacizumab; cisplatin; doxorubicin; erlotinib; fluorouracil; interferon; drug efficacy; monotherapy; multimodality cancer therapy; patient selection; treatment duration; treatment planning; unspecified side effect; conference paper; capecitabine; gemcitabine; adjuvant therapy; cancer adjuvant therapy; pancreas cancer; pancreas resection; combined modality therapy; pancreatic neoplasms; chemotherapy; cancer staging; nuclear magnetic resonance imaging; neoplasm staging; evidence based medicine; cancer palliative therapy; quality control; quality of life; computer assisted tomography; multiple cycle treatment; radiotherapy; combination chemotherapy; cancer pain; patient monitoring; practice guideline; continuous infusion; cetuximab; survival time; patient care; liver metastasis; folinic acid; nonsteroid antiinflammatory agent; pancreas tumor; health care personnel; psychosocial care; stent; mitomycin c; visceral metastasis; platinum derivative; pancreas enzyme; pancreatic cancer; bile duct obstruction; morphine; cancer classification; oxaliplatin; endoscopic echography; streptozocin; drug choice; spain; duodenum obstruction; adjuvant treatment; morphine derivative |
| Journal Title: | Annals of Oncology |
| Volume: | 18 |
| Issue: | SUPPL. 7 |
| ISSN: | 0923-7534 |
| Publisher: | Oxford University Press |
| Date Published: | 2007-06-01 |
| Start Page: | vii1 |
| End Page: | vii10 |
| Language: | English |
| DOI: | 10.1093/annonc/mdm210 |
| PUBMED: | 17600091 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 30" - "Export Date: 17 November 2011" - "CODEN: ANONE" - "Source: Scopus" |
