Maximal cytoreductive effort in epithelial ovarian cancer surgery Journal Article


Authors: Shih, K. K.; Chi, D. S.
Article Title: Maximal cytoreductive effort in epithelial ovarian cancer surgery
Abstract: The surgical management of advanced epithelial ovarian cancer involves cytoreduction, or removal of grossly-evident tumor. Residual disease after surgical cytoreduction of ovarian cancer has been shown to be strongly associated with survival. The goal of surgery is "optimal" surgical cytoreduction, which is generally defined as residual disease of 1 cm or less. However, the designation of "optimal" surgical cytoreduction has evolved to indude maximal surgical effort and no gross residual disease. In order to achieve this, more aggressive surgical procedures such as rectosigmoidectomy, diaphragm peritonectomy, partial liver resection, and video-assisted thoracic surgery are reported and increasingly utilized in the surgical management of advanced ovarian cancer. The role of maximal surgical effort also extends to the recurrent setting where the goal of surgery should be complete cytoreduction. Patient selection is important in identifying appropriate candidates for surgical cytoreduction in the recurrent setting. The purpose of this artide is to review the role of maximum surgical effort in primary and recurrent ovarian cancer.
Keywords: cancer chemotherapy; cancer survival; treatment outcome; cancer surgery; surgical technique; review; cancer recurrence; advanced cancer; patient selection; cancer staging; antineoplastic agent; ovarian cancer; cytoreductive surgery; ovary cancer; cancer size; platinum; cytoreduction; diaphragm peritonectomy; rectosigmoidectomy; sigmoidectomy
Journal Title: Journal of Gynecologic Oncology
Volume: 21
Issue: 2
ISSN: 2005-0380
Publisher: Korean Soc Gynecology Oncology & Colposcopy  
Date Published: 2010-06-01
Start Page: 75
End Page: 80
Language: English
DOI: 10.3802/jgo.2010.21.2.75
PROVIDER: scopus
PMCID: PMC2895720
PUBMED: 20613895
DOI/URL:
Notes: --- - "Cited By (since 1996): 4" - "Export Date: 20 April 2011" - "Source: Scopus"
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MSK Authors
  1. Dennis S Chi
    710 Chi
  2. Karin Kuan-Hui Shih
    41 Shih
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