Granuloma of the membranous vocal fold: An unusual complication of microlaryngoscopic surgery Journal Article


Authors: Sulica, L.; Simpson, C. B.; Branski, R.; McLaurin, C.
Article Title: Granuloma of the membranous vocal fold: An unusual complication of microlaryngoscopic surgery
Abstract: Objectives: We describe the clinical features of granuloma of the membranous vocal fold (as opposed to granuloma of the vocal processor "contact granuloma"), a poorly recognized sequela of microlaryngoscopic surgery. Membranous vocal fold granuloma may mimic the initial lesion in appearance, and thus be mistaken for recurrence. Methods: We performed a retrospective review of cases from 2 institutions. Results: Fifteen cases of membranous vocal fold granuloma from 2 institutions were identified. In all but 1 case, granuloma developed in the early postoperative period, within 8 weeks. Of the 15 cases, 10 followed laser resection of carcinoma. Five were noted following cold steel resection of benign lesions (2 papillomas, 2 cysts, 1 Reinke's edema). Technical aspects of these cases suggest that membranous vocal fold granulomas result from surgical violation of deep tissue planes and/or epithelial defects. All patients were treated with proton pump inhibitors. In 12 cases, the granulomas proved self-limited, resolving over weeks to months following surgery. Three patients underwent surgical removal of the lesion, which confirmed the diagnosis. One of these cases recurred and was treated nonsurgically. Conclusions: Granuloma should be suspected when a mass lesion appears at the surgical site early in the postoperative course. Surgical excision is generally not necessary and may provoke further growth of granulation tissue. © 2007 Annals Publishing Company. All rights reserved.
Keywords: adult; clinical article; controlled study; aged; aged, 80 and over; middle aged; retrospective studies; clinical feature; postoperative period; vocal cord; skin defect; steroid; retrospective study; proton pump inhibitor; vocal fold; vocal cords; laser surgery; larynx cancer; laryngeal diseases; omeprazole; granuloma; larynx surgery; microlaryngoscopy; laryngoscopy; cyst; granulation tissue; institutional care; lansoprazole; esomeprazole; steel; larynx edema; larynx granuloma; larynx papillomatosis; proton pumps
Journal Title: Annals of Otology Rhinology and Laryngology
Volume: 116
Issue: 5
ISSN: 0003-4894
Publisher: Annals Publ Co  
Date Published: 2007-05-01
Start Page: 358
End Page: 362
Language: English
PUBMED: 17561764
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 17 November 2011" - "CODEN: AORHA" - "Source: Scopus"
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MSK Authors
  1. Ryan C Branski
    22 Branski