Multi-class medical image segmentation using one-vs-rest graph cuts and majority voting Journal Article


Authors: Hu, Y. C.; Mageras, G.; Grossberg, M.
Article Title: Multi-class medical image segmentation using one-vs-rest graph cuts and majority voting
Abstract: Purpose: Semi-automatic image segmentation is still a valuable tool in clinical applications since it retains the expert oversights legally required. However, semi-automatic methods for simultaneous multi-class segmentation are difficult to be clinically implemented due to the complexity of underlining algorithms. We purpose an efficient one-vs-rest graph cut approach of which the complexity only grows linearly as the number of classes increases. Approach: Given an image slice, we construct multiple one-vs-rest graphs, each for a tissue class, for inference of a conditional random field (CRF). The one-vs-rest graph cut is to minimize the CRF energy derived from regional and boundary class probabilities estimated from random forests to obtain a one-vs-rest segmentation. The final segmentation is obtained by fusing from those one-vs-rest segmentations based on majority voting. We compare our method to a well-used multi-class graph cut method, alpha-beta swap, and a fully connected CRF (FCCRF) method, in brain tumor segmentation of 20 high-grade tumor cases in 2013 MICCAI dataset. Results: Our method achieved mean Dice score of 0.83 for whole tumor, compared to 0.80 by alpha-beta swap and 0.79 by FCCRF. There was a performance improvement over alpha-beta swap by a factor of five. Conclusions: Our method utilizes the probabilistic-based CRF which can be estimated from any machine learning technique. Comparing to traditional multi-class graph cut, the purposed one-vs-rest approach has complexity that grows only linearly as the number of classes increases, therefore, our method can be applicable for both online semi-automatic and offline automatic segmentation in clinical applications. © 2021 Society of Photo-Optical Instrumentation Engineers (SPIE).
Keywords: automation; tumors; decision trees; clinical application; image segmentation; semi-automatic segmentation; graphic methods; automatic segmentations; learning systems; random processes; graph cuts; machine learning techniques; medical image processing; conditional random field; brain tumor segmentation; multi-class segmentation; computational complexity; multi-class segmentations; semi-automatic image segmentation; semiautomatic methods
Journal Title: Journal of Medical Imaging
Volume: 8
Issue: 3
ISSN: 2329-4302
Publisher: SPIE  
Date Published: 2021-05-01
Start Page: 034003
Language: English
DOI: 10.1117/1.Jmi.8.3.034003
PROVIDER: scopus
PMCID: PMC8223166
PUBMED: 34179219
DOI/URL:
Notes: Article -- Export Date: 2 August 2021 -- Source: Scopus
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MSK Authors
  1. Gikas S Mageras
    277 Mageras
  2. Yu-Chi Hu
    118 Hu
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